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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Cell Lines

Cell Lines

A cell line is a population of cells grown in vitro that can be subcultured over several generations. Normal cells cease to divide after a certain number of cell divisions, a process known as replicative senescence. This number, called the Hayflick limit, was conceptualized by Leonard Hayflick in 1961 when he observed that fetal cells grown in culture could only divide 40-60 times. This limit is due to the shortening of the telomeres during each round of cell division, preventing cell division...

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Related Experiment Video

Updated: Jun 8, 2026

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

A Method for Lineage Tracing of Corneal Cells Using Multi-color Fluorescent Reporter Mice

Published on: December 18, 2015

Stem cell banking: between traceability and identifiability.

Bartha M Knoppers¹, Rosario Isasi

¹Centre of Genomics and Policy, McGill University, 740 Dr Penfield Avenue, Suite 5206, Montreal, QC, H3A 1A4, Canada. bartha.knoppers@mcgill.ca.

Genome Medicine

|October 7, 2010

Summary

This summary is machine-generated.

Stem cell banks are vital for research and the bioeconomy. Harmonizing policies and practices with general biobanking lessons can improve stem cell banking operations.

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Area of Science:

Biotechnology
Regenerative Medicine
Biobanking

Background:

Stem cell banks are crucial for research, providing quality-controlled, ethically sourced stem cell lines.
Advancements in regenerative medicine are driving the development of a bioeconomy, positioning stem cell banks as key economic pillars.
Stem cell banking can benefit from established practices in tissue and data banking to enhance interoperability.

Purpose of the Study:

To analyze the convergence and divergence of issues in stem cell banking.
To explore policy harmonization, transnational sharing, informed consent, traceability, and return of results.
To leverage lessons learned from general biobanking for stem cell banking.

Main Methods:

Comparative analysis of stem cell banking and general biobanking practices.
Examination of policy frameworks related to ethical and legal concerns.
Review of international approaches to consent and traceability.

Main Results:

Identified commonalities and differences between stem cell banking and broader biobanking.
Highlighted the importance of harmonized policies for transnational sharing and interoperability.
Emphasized the critical role of informed consent and traceability in stem cell banking.

Conclusions:

Stem cell banks must adopt best practices from general biobanking to ensure ethical and efficient operations.
Policy harmonization and international collaboration are essential for advancing stem cell research and the bioeconomy.
Lessons learned in consent and traceability from biobanking offer valuable guidance for stem cell banking.