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Mucorales and deferoxamine: from saprophytic to pathogenic state
L Vandevelde1, C Bondewel, M Dubois
1ENT Dept., Brugmann University Hospital.
Acta Oto-Rhino-Laryngologica Belgica
|January 1, 1990
Summary
Rhinocerebral mucormycosis is a dangerous fungal infection. This case highlights how Deferoxamine may promote mucormycosis in dialysis patients, emphasizing the need for early diagnosis to improve survival rates.
Area of Science:
- Medicine
- Infectious Diseases
- Nephrology
Background:
- Rhinocerebral mucormycosis is a severe fungal infection with a high mortality rate, especially when treatment is delayed.
- Long-term dialysis patients are a vulnerable population for opportunistic infections.
- Deferoxamine, a siderophore, has been implicated in promoting fungal growth in certain conditions.