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γ-Oxygenation of α,β-unsaturated esters by vinylogous O-nitroso Mukaiyama aldol reaction
Guo-Qiang Tian1, Jiong Yang, Kellymar Rosa-Perez
1Department of Chemistry, Texas A&M University, College Station, Texas 77843-3255, United States.
Abstract:
A practical procedure has been developed for γ-oxygenation of α,β-unsaturated esters by a vinylogous O-nitroso Mukaiyama aldol reaction followed by a one-pot N-O bond heterolysis of the in situ generated γ-aminoxy-α,β-unsaturated esters.
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