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Imaging Replicative Domains in Ultrastructurally Preserved Chromatin by Electron Tomography
Published on: May 20, 2022
Reconstruction convergence and speed enhancement in electrical impedance tomography for domains with known internal
Saeed Rezajoo1, Gholam-Ali Hossein-Zadeh
1Control and Intelligent Processing Center of Excellence, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran. rezajoo@ut.ac.ir
Abstract:
An improved approach for electrical impedance tomography (EIT) image reconstruction, based on modifying the forward and inverse solutions, is proposed. In this approach, the EIT forward problem is solved via the finite element method (FEM) using two types of elements. The inverse problem is solved by the modified Newton-Raphson method, whereas the condition number of the Hessian matrix is being monitored. At the early stage of the reconstruction, first-order elements are used, and if the condition number exceeds the allowable limit, the algorithm restarts. Otherwise, if the reconstruction error becomes lower than a predefined threshold, second-order elements are employed in the forward solution in order to preserve the precision of the final results. The latter stage converges in very few iterations. Since the solution speed with the first-order FEM is considerably higher than the second-order FEM, the reconstruction speed improves considerably by this approach, whereas the accuracy of the results is guaranteed by the well-conditioned Hessian matrix. Numerical simulations and experiments are followed by comparisons with other reconstruction methods which demonstrate the reliability and high solution speed of this approach. According to the results, the convergence of the proposed method is significantly improved, and its speed is 2-200 times higher than the previously developed methods with the same level of precision.
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