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The AIDS and Cancer Specimen Resource
Leona W Ayers1, Sylvia Silver, Jan M Orenstein
1Department of Pathology, College of Medicine and Public Health, The Ohio State University, Columbus, OH, USA.
Methods in Molecular Biology (Clifton, N.J.)
|October 16, 2010
Summary
The AIDS and Cancer Specimen Resource (ACSR) provides over 265,000 HIV-related human tissue and fluid samples to researchers. This resource supports studies on HIV/AIDS malignancies, offering free access to valuable biospecimens and technical assistance.
Area of Science:
- Virology
- Oncology
- Biorepository Science
Background:
- The AIDS and Cancer Specimen Resource (ACSR) is a collaborative initiative funded by the National Cancer Institute (NCI).
- It focuses on collecting and distributing HIV-related human tissues and biological fluids for research into HIV/AIDS-related malignancies.
Purpose of the Study:
- To provide qualified investigators with access to a comprehensive biorepository of HIV-positive and control samples.
- To facilitate research on HIV/AIDS-related cancers through the provision of biospecimens and technical support.
Main Methods:
- Collection, preservation, and distribution of over 265,000 human HIV-positive and control samples.
- Provision of technical support, including HIV DNA identification and tissue microarray (TMA) block preparation.
- Facilitation of research through cooperative arrangements for unmet material needs.
Main Results:
- A biorepository containing samples from 39 processing types, 16 specimen types, and 52 anatomical sites.
- Free access to HIV-infected biological fluids and tissues for funded, approved investigators.
- Contribution of 117 scientific reports and 94 publications to the scientific literature (as of 2010).
Conclusions:
- The ACSR serves as a critical resource for advancing research in HIV/AIDS-related malignancies.
- The availability of diverse biospecimens and support services accelerates scientific discovery in the field.
- Investigators are encouraged to utilize the ACSR's online catalog for their research needs.
