Related Experiment Video
Updated: Jun 8, 2026
06:22
Neonatal Pial Surface Electroporation
Published on: May 7, 2014
[Treatment of infants with Pierre Robin sequence]
1Zentrum für kindliche Fehlbildungen im Kiefer- und Gesichtsbereich (ZKFKG), Tübingen, Germany.
Laryngo- Rhino- Otologie
|October 16, 2010
Summary
Pierre Robin sequence (PRS) can cause airway obstruction, potentially impacting neurodevelopment. A new non-invasive intraoral appliance offers an effective treatment to mitigate these risks.
Area of Science:
- Craniofacial anomalies
- Pediatric airway obstruction
- Developmental disorders
Context:
- Pierre Robin sequence (PRS) is a congenital condition characterized by mandibular hypoplasia, glossoptosis, and often cleft palate.
- Upper airway obstruction (UAO) is a significant clinical manifestation in PRS, posing risks to neurodevelopment.
- Existing treatments for UAO in PRS include invasive and non-invasive methods with varying efficacy.
Purpose:
- To present a novel, non-invasive treatment protocol for managing upper airway obstruction in Pierre Robin sequence.
- To evaluate the efficacy of an intraoral orthodontic appliance with a pre-epiglottic baton plate (PEBP) in resolving UAO.
Summary:
- The article describes an effective, non-invasive treatment protocol for Pierre Robin sequence (PRS)-related upper airway obstruction (UAO).
- This protocol utilizes an intraoral orthodontic appliance with a velar extension, specifically the pre-epiglottic baton plate (PEBP).
- PRS, affecting approximately 1:8,500 births, involves mandibular retrognathia and glossoptosis, leading to UAO and potential neurocognitive impairment if unaddressed.
Impact:
- This innovative PEBP appliance offers a promising alternative to more invasive procedures for managing UAO in PRS.
- Early and effective intervention can reduce the risk of neurocognitive impairment in infants with PRS.
- The non-invasive nature of the PEBP may improve patient comfort and reduce treatment-related complications.
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