Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Graves Disease II: Pathophysiology

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...

Cirrhosis I: Introduction

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...

Cranial Bones: Lateral View

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...

Hyperthyroidism II: Pathophysiology

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...

Assessment of the Cardiovascular System II: Inspection

Assessment of the Cardiovascular System II: Inspection

Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Study of inborn errors of immunity associated lymphoid proliferations identifies association of presence of somatic variations with large cell morphology, copy number alterations in TNFAIP3 and heterozygous variants in EMSY.

Virchows Archiv : an international journal of pathology·2026

Same author

Expression and prognostic value of cytotoxic T-lymphocyte-associated 4 protein in classic Hodgkin lymphoma.

Expert review of hematology·2026

Same author

Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2024

Same author

Rare case of aspergillosis with solitary renal involvement: micro-fungus ball in graft kidney.

CEN case reports·2024

Same author

Indolent B-cell non-Hodgkin lymphomas in children: high association with inborn errors of immunity.

Leukemia & lymphoma·2024

Same author

Is it Possible to Obtain Immunofluorescence Data in Formalin-Fixed Paraffin-Embedded Skin Samples for the Diagnosis of Pemphigus Vulgaris and Bullous Pemphigoid.

Turk patoloji dergisi·2023

Search research articles

Related Experiment Video

Updated: Jun 7, 2026

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

Published on: May 18, 2022

Bilateral Temporal Bone Xanthomas in Type II Hypercholesterolemia.

Cezmi Turk¹, Burcak Bılgıner, Kemal Benlı

¹Hacettepe University, School of Medicine, Department of Neurosurgery, Ankara, Turkey.

Turkish Neurosurgery

|October 22, 2010

Summary

This rare intracranial xanthoma case involved both temporal bones, damaging mastoid air cells and compressing the cerebellum. Surgical removal of the lesion was successful.

More Related Videos

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

Related Experiment Videos

Last Updated: Jun 7, 2026

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

High-Speed Human Temporal Bone Sectioning for the Assessment of COVID-19-Associated Middle Ear Pathology

Published on: May 18, 2022

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

Area of Science:

Neurology
Neurosurgery
Pathology

Background:

Intracranial xanthomas are rare tumors characterized by lipid accumulation.
Temporal bone involvement is exceptionally uncommon, posing diagnostic and surgical challenges.

Observation:

A rare case of intracranial xanthoma with bilateral temporal bone involvement is presented.
The lesion demonstrated significant destructive and remodeling effects on the mastoid air cells.
Cerebellar compression was evident on the right side due to the lesion's mass effect.

Findings:

Histopathological examination confirmed the diagnosis of xanthoma.
Surgical intervention on the symptomatic side resulted in complete lesion resection.
Post-operative recovery was uneventful, with resolution of neurological deficits.

Implications:

This case highlights the importance of considering rare pathologies in complex intracranial lesions.
Early surgical intervention is crucial for managing symptomatic intracranial xanthomas.
Further research into the pathogenesis and optimal management of intracranial xanthomas is warranted.