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Epidemiologic insights into pediatric kidney stone disease
Brian R Matlaga1, Anthony J Schaeffer, Thomas E Novak
1James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Park 2, 600 North Wolfe Street, Baltimore, MD 21287, USA. bmatlaga@jhmi.edu
Urological Research
|October 23, 2010
Summary
Pediatric kidney stones show a changing gender prevalence with age and increased incidence from 1997-2003. Younger children with stones often have diabetes and hypertension, indicating a complex systemic disease.
Area of Science:
- Pediatric Nephrology
- Epidemiology of Urolithiasis
- Public Health
Background:
- Pediatric kidney stone disease epidemiology is less defined than adult disease.
- Characterizing pediatric stone disease is crucial for understanding its unique aspects.
- Previous studies have not fully elucidated age- and gender-specific trends or comorbidities.
Purpose of the Study:
- To characterize the epidemiology of pediatric kidney stone disease.
- To investigate age and gender distribution, prevalence changes, and associated medical comorbidities.
- To utilize the Kids' Inpatient Database (KID) for robust analysis.
Main Methods:
- Utilized the Kids' Inpatient Database (KID) for patient identification.
- Identified pediatric patients with renal and ureteral calculi using ICD-9 codes.
- Employed specific comorbidity software and performed statistical comparisons.
Main Results:
- Stone prevalence was higher in males in the first decade and females in the second decade of life.
- A significant increase in treated stone disease was observed between 1997 and 2003 for both genders.
- Kidney stones in children under 6 were associated with hypertension and diabetes mellitus.
Conclusions:
- Pediatric kidney stone disease exhibits a complex, age-dependent gender distribution.
- Overall, females have a higher prevalence of kidney stones than males.
- Urolithiasis in young children is linked to systemic conditions like diabetes and hypertension, suggesting a complex disease process.
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