Related Experiment Video
Updated: Jun 7, 2026

09:00
Olfactory Behavioral Testing in the Adult Mouse
Published on: January 28, 2009
Olfactory neuroblastoma in a cat.
Valerie J Parker1, Jo Ann Morrison, Michael J Yaeger
1Iowa State University, College of Veterinary Medicine, 1600 South 16th Street, Ames, IA 50011-1250, USA. vparker@iastate.edu
Journal of Feline Medicine and Surgery
|October 27, 2010
Summary
Olfactory neuroblastoma, a rare nasal tumor in cats, can be challenging to diagnose. This case highlights the importance of considering this diagnosis in cats with upper airway disease.
Area of Science:
- Veterinary Oncology
- Comparative Pathology
Background:
- Olfactory neuroblastoma (esthesioneuroblastoma) is a rare malignant neoplasm originating from olfactory neuroepithelium.
- First described in human medicine in 1924, it presents diagnostic challenges in veterinary patients.
Observation:
- A 12.5-year-old domestic shorthair cat presented with dyspnea and was found to have a nasopharyngeal mass via CT scan.
- Biopsies confirmed the mass as olfactory neuroblastoma, a differential for intranasal tumors in cats.
Findings:
- Clinical signs of olfactory neuroblastoma are variable and can mimic other feline upper airway or intranasal tumors.
- This rare tumor is often mistaken for poorly differentiated carcinomas or round cell tumors.
Implications:
- Accurate diagnosis of olfactory neuroblastoma is crucial for appropriate management in cats.
- Further research into treatment options and prognostic factors is needed due to the lack of established protocols.
