Related Experiment Video
Updated: Jan 15, 2026

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
A Quick Reference on Hypocalcemia
Valerie J Parker1, Dennis J Chew1
1Department of Veterinary Clinical Sciences, The Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43210, USA.
Abstract:
This article discusses calcium homeostasis, emphasizing the importance of ionized calcium (iCa) as the active form regulated primarily by parathyroid hormone, vitamin D, and other factors. It highlights causes of hypocalcemia, including renal, gastrointestinal, and endocrine disorders, and notes that clinical signs-such as neuromuscular excitability and cardiac arrhythmias-often depend on severity and rapidity of onset. Diagnosis involves measuring serum and ionized calcium, with treatment focusing on correcting underlying causes and carefully restoring iCa levels, especially in animals with seizures or severe clinical signs. Monitoring and avoiding overcorrection are essential for effective management.
More Related Videos
Related Concept Videos
Skeleton and Calcium Homeostasis
Synthesis and Functions of Calcitonin
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
Hypoglycemia and Glucagon
Introduction to Electrolytes
Role of Sodium
One...
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
SBAR II: Application of SBAR
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...

