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Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

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Related Experiment Video

Updated: Jun 7, 2026

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

Beware of neonatal appendicitis.

Rizwan A Khan¹, Prema Menon, K L N Rao

¹Department of Pediatric Surgery, PGIMER, Chandigarh, India.

Journal of Indian Association of Pediatric Surgeons

|October 27, 2010

Summary

Neonatal appendicitis can be mistaken for necrotizing enterocolitis, posing a diagnostic challenge. Early recognition and considering appendicitis are crucial for prompt treatment in newborns.

Area of Science:

Neonatal Medicine
Pediatric Surgery

Background:

Neonatal necrotizing enterocolitis (NEC) is a common gastrointestinal emergency in premature infants.
Acute appendicitis is exceedingly rare in neonates, presenting diagnostic challenges.

Observation:

A neonate was initially diagnosed with and treated for NEC.
The neonate actually had acute appendicitis, highlighting a diagnostic error.

Findings:

Appendicitis in neonates can mimic NEC, leading to delayed diagnosis.
This case underscores the importance of considering rare differential diagnoses.

Implications:

Increased awareness of neonatal appendicitis is vital for timely surgical intervention.
Developing improved diagnostic strategies for neonatal abdominal emergencies is necessary.

Keywords:

Appendicitis necrotizing enterocolitis neonate peritonitis

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