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Published on: August 14, 2019
Diffusion tensor imaging of chronic right cerebral hemisphere infarctions
Eeva Jason1, Prasun Dastidar, Antti Kalliokoski
1Imaging Center of the Pirkanmaa Hospital District, Department of Diagnostic Radiology, Tampere University Hospital, Tampere, Finland. eeva.jason@uta.fi
Summary
Diffusion tensor imaging (DTI) reveals changes after right cerebral hemisphere infarction. Patients with visible wallerian degeneration (WD) or hemorrhagic transformation (HT) show altered DTI parameters and worse neurological outcomes.
Area of Science:
- Neuroimaging
- Radiology
- Neurology
Background:
- Diffusion tensor imaging (DTI) is crucial for assessing white matter integrity.
- Understanding chronic stroke changes, including wallerian degeneration (WD) and hemorrhagic transformation (HT), is vital for prognosis.
Purpose of the Study:
- To characterize DTI findings in right cerebral hemisphere infarctions.
- To investigate differences in DTI parameters and neurological status in patients with visible WD or HT in the chronic stage.
Main Methods:
- DTI was performed on 25 stroke patients.
- Fractional anisotropy (FA) and mean diffusivity (MD) were measured across multiple brain regions.
- Neurological scores were assessed, and subgroup analyses for WD and HT were conducted.
Main Results:
- Increased MD and decreased FA were observed in the affected hemisphere compared to the contralateral side.
- Patients with WD had worse chronic Rankin Scale scores and distinct DTI parameters.
- Patients with HT had lower chronic Barthel Index scores and reduced thalamic FA.
Conclusions:
- DTI effectively identifies post-infarction changes in both the lesion site and distant areas.
- Visible WD or HT correlates with more significant DTI alterations and poorer patient outcomes.
