[Endometrial cancer. A clinico-morphological study]

Knowledge of cyclic changes, connected with hormonal action and precancerous states, is of substantial significance for early diagnosis and timely treatment of endometrial carcinoma. Eighty six women with endometrial carcinoma, established histologically, were studied prospectively. A parallel study of histological differentiation of the tumour and some clinical symptoms was made. Serum level of F2 were examined as well. It was found that they were more manifested in highly differentiated adenocarcinomas. Women with histories for dysfunctional uterine bleedings suffering from hypertonic disease diabetes, obesity and with increased levels of E2 were considered as a risk group for development of endometrial carcinoma.