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Updated: Jun 7, 2026

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase
Published on: April 4, 2025
[Leishmaniasis isolated to the larynx as cause of chronic laryngitis]
Mikkel Kaltoft1, Helga Richert Munch-Petersen, Henrik Møller
1Gentofte Hospital, Øre-naese-halskirurgisk Afdeling E, Denmark. mikkelkaltoft@dadlnet.dk
Abstract:
Mucosal leishmaniasis is uncommon outside Central and South America, where it is commonly caused by Leishmania (L.) braziliensis. We present a case of isolated laryngeal leishmaniasis detected in a 78-year-old male, who presented with chronic hoarseness. Histologic examination of biopsies taken from the larynx showed L. amastigotes. An L.-specific indirect fluorescent antibody test was positive. Polymerase chain reaction showed infection with L. donovani, L. infantum or L. tropica, species which do not normally cause isolated mucosal infection. This is the first reported case from Scandinavia.
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