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Updated: Jun 7, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
[Periodontitis is one of the most commonly occurring inflammatory diseases]
Palle Holmstrup1, Jesper Reinholdt, Anne Havemose Poulsen
1Københavns Universitet, Afdeling for Parodontologi, Københavns Tandlaegeskole, 2200 København N, Denmark. pah@sund.ku.dk
Abstract:
Periodontitis is a common inflammatory disease characterized by breakdown of the structure supporting the tooth. The disease, which is caused by bacteria colonizing the root surface, occurs with a marked difference in individual susceptibility and presents as chronic and aggressive forms of the disease. A number of medical disorders act as predisposing factors, and periodontitis may influence the course of some diseases, including coronary heart disease and diabetes.
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