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Related Concept Videos

Hypothyroidism II: Pathophysiology01:23

Hypothyroidism II: Pathophysiology

Hypothyroidism is a disorder characterized by insufficient production of thyroid hormones, which regulate metabolism, energy balance, and multiple organ systems.TypesHypothyroidism is classified based on the level of dysfunction. Primary hypothyroidism results from intrinsic thyroid gland dysfunction, causing reduced hormone production despite normal or increased stimulation. Secondary hypothyroidism arises from inadequate thyroid-stimulating hormone (TSH) secretion by the pituitary. Tertiary...
Hyperthyroidism II: Pathophysiology01:27

Hyperthyroidism II: Pathophysiology

Hyperthyroidism is a hypermetabolic state caused by elevated levels of thyroid hormones, triiodothyronine (T3) and thyroxine (T4). It results from dysregulation at the thyroid, pituitary, or immune system level and affects multiple organ systems.PathophysiologyThe most common cause of hyperthyroidism is Graves’ disease, an autoimmune disorder in which antibodies, specifically thyroid-stimulating antibodies (TSAb), a subtype of TSH receptor antibodies (TRAb), bind to and activate TSH receptors...
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Hyperthyroidism I: Introduction01:25

Hyperthyroidism I: Introduction

Hyperthyroidism is a type of thyrotoxicosis characterized by the thyroid gland's overproduction of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). This hormone excess increases the basal metabolic rate and enhances sensitivity to catecholamines.DiagnosisDiagnosis is based on clinical features and biochemical testing. It typically shows suppressed thyroid-stimulating hormone (TSH) levels below 0.4 mIU/L, with elevated free T3 and/or T4. Additional tests, including thyroid...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...

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An Acupoint Catgut-embedding Therapy for Treating Obesity
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[Thyroid function and obesity].

L Garnerone1, L Iorio, R Zelaschi

  • 1Unità Operativa di Endocrinologia e Diabetologia, Dipartimento di Scienze Medico-Chirurgiche, IRCCS Policlinico San DonatoUniversità degli Studi di Milano, Milano, Italia.

Minerva Medica
|November 5, 2010
PubMed
Summary
This summary is machine-generated.

The connection between thyroid function and obesity is complex, potentially involving insulin resistance. More research is needed to understand how normal thyroid hormone levels affect body weight and vice versa.

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Multidisciplinary Approach to Obesity Management: A Case Report
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Area of Science:

  • Endocrinology
  • Metabolic Health
  • Obesity Research

Context:

  • The interplay between thyroid function and obesity is not fully understood.
  • Insulin resistance is a key factor potentially linking thyroid hormones and body weight.
  • Existing research lacks clarity on whether thyroid hormone variations within the normal range impact body weight or if obesity affects thyroid function.

Purpose:

  • To explore the complex relationship between thyroid function and obesity.
  • To investigate the influence of thyroid-stimulating hormone (TSH) and thyroid hormones on body weight.
  • To determine if obesity can alter thyroid function.

Summary:

  • Thyroid function is associated with body mass index (BMI), body composition, and fat mass percentage.
  • Further studies are required to clarify the bidirectional relationship between thyroid function and body weight.
  • Future research should consider body fat distribution, obesity duration, and low-grade inflammation alongside thyroid hormone levels.

Impact:

  • Highlights the need for comprehensive studies examining thyroid function and obesity.
  • Emphasizes the importance of considering multiple factors beyond simple BMI in obesity research.
  • Provides a foundation for future research into metabolic health and endocrine disorders.