Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Development of the Limb Synovial Joints

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Generative Artificial Intelligence for Orthognathic Planning: Patient-Specific 3-Dimensional Jaw Reference Forms Conditioned on the Cranial Base.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2026

Same author

A Tibial Osteotomy of the Medial Collateral Ligament Insertion to Improve Visualization of the Medial Tibial Plateau: A Cadaveric Study.

Journal of orthopaedic trauma·2026

Same author

Facial appearance prediction for orthognathic surgery with diffusion models.

Medical image analysis·2026

Same author

The Kindred Reference Form: A New Paradigm for Assessing Facial Morphology in Patients With Deformities.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons·2026

Same author

AI-Assisted Soft Tissue Virtual Planning in Computer-Assisted Jaw Reconstruction with Fibula Free Flaps.

Plastic and reconstructive surgery·2025

Same author

Accuracy of femoral head center reconstruction using a straight cementless rectangular stem: An <i>in-silico</i> study comparing elderly and middle-aged patients.

Journal of orthopaedics·2025

Search research articles

Related Experiment Video

Updated: Jun 7, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

Development of a mandibular motion simulator for total joint replacement.

Nukhet Celebi¹, E Carlos Rohner, Jaime Gateno

¹Department of Oral and Maxillofacial Surgery, The Methodist Hospital Research Institute, Houston, TX, USA.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons

|November 6, 2010

Summary

A novel motion simulator recreates full mandibular motion in cadavers before and after temporomandibular joint (TMJ) replacement. This technology aids in analyzing limited jaw movement post-surgery and developing improved treatment strategies.

More Related Videos

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

Related Experiment Videos

Last Updated: Jun 7, 2026

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

Area of Science:

Biomechanical Engineering
Oral and Maxillofacial Surgery
Medical Device Development

Background:

The temporomandibular joint (TMJ) is crucial for complex mandibular movements.
Understanding TMJ biomechanics is essential for treating joint disorders and evaluating prosthetics.
Current methods for analyzing jaw motion may not fully capture the dynamics of intact and replaced TMJs.

Purpose of the Study:

To develop a sophisticated motion simulator for recreating and recording comprehensive mandibular motions.
To assess jaw movement in a cadaveric model with an intact TMJ and after total joint replacement.

Main Methods:

Utilized a human cadaver head with tracking balls on the forehead and mandible.
Generated realistic jaw motions via simulated muscle forces (lateral pterygoid, suprahyoid, elevator muscles).
Recorded mandibular movements using a high-resolution laser scanner and created 3D CT models.

Main Results:

Successfully recreated and recorded mandibular motions in a cadaveric preparation before and after TMJ replacement.
Observed significantly limited lateral and protrusive mandibular motions post-TMJ replacement.
Identified condylar component sinking into the fossa during jaw motion after prosthesis implantation.

Conclusions:

Developed a functional motion simulator for analyzing intact and replaced TMJs.
The simulator enables detailed motion path analysis and investigation into causes of restricted movement.
Provides a platform for evaluating and improving total joint replacement strategies for the TMJ.