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Updated: Jun 7, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Pleuroscopy for diagnosis and therapy for pleural effusions
Gaetane Michaud1, David M Berkowitz, Armin Ernst
1Interventional Pulmonology and Thoracic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, One Deaconess Rd, Deaconess 201A, Boston, MA 02215, USA. gmichaud@bidmc.harvard.edu
Pleuroscopy, a minimally invasive procedure, offers high diagnostic accuracy for pleural effusions and allows therapeutic interventions like chemical pleurodesis with low complication rates.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Minimally Invasive Procedures
Background:
- Pleuroscopy, or medical thoracoscopy, is a diagnostic and therapeutic tool for pleural space conditions.
- It can be performed under moderate sedation without intubation, differentiating it from video-assisted thoracic surgery.
Purpose of the Study:
- To evaluate the diagnostic accuracy and therapeutic efficacy of pleuroscopy.
- To assess the safety and complication rates associated with the procedure.
Main Methods:
- Review of pleuroscopy procedures for pleural space inspection, biopsy, and therapeutic interventions.
- Analysis of diagnostic yield in malignant and tuberculous pleural effusions.
- Assessment of complication and mortality rates.
Main Results:
- Diagnostic accuracy approaches 100% for malignant and tuberculous pleural effusions.
- Low complication rates (2%-5%) with minor issues; mortality rates are <0.1%.
- Therapeutic interventions, such as chemical pleurodesis, show success rates near 90% for malignant pleural effusions.
Conclusions:
- Pleuroscopy is a safe and well-tolerated procedure when performed by trained professionals.
- It demonstrates high diagnostic accuracy and therapeutic efficacy for pleural space disorders.
- The procedure offers a valuable minimally invasive option for managing complex pleural effusions.
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