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[Morphological characteristics of meningiomas]
Maja Grujicić1, Nada Vucković, Petar Vuleković
1Medicinski fakultet, Novi Sad. grujicic@uns.ac.rs
Introduction:
Meningiomas are common intracranial neoplasms which originate from the soft meninges, precisely from meningeal arachnoidal cells. The aim of this investigation was to establish the age and sex distribution of the examinees, localization, frequency and histological types of meningiomas.
Material And Methods:
The investigation was carried out in the period from January 2001 to June 2006. It included 490 consecutive patients of both sexes with diagnosed intracranial tumors and undergoing surgical treatment at the Neurosurgery Clinic of the Clinical Center of Vojvodina. The surgery samples were analyzed in the Laboratory of the Institute of Pathology and Histology of the Clinical Center of Vojvodina. Out of 490 patients with diagnosed intracranial tumors, 137 (27.96%) were diagnosed to have meningiomas.
Results:
Meningiomas were more frequent in females (63%) than in males (37%) and they were most common in the 50-59 year age group (37.2%). The most common localization of meningiomas was the frontal region (36.5%). Meningiomas were more common on the left side (44.5%). In regard to other histological types of intracranial tumors, meningiomas were more frequent in females (36.3%). The most common histological type of meningiomas was transitional meningiomas (59.1%). The commonest histological types of meningiomas were benign meningiomas (93.4%). Malignant histological types of meningiomas were more common in males (83.3%), whereas benign histological types were more common in females (64.1%).
Conclusion:
A typical patient with meningiomas is a woman 50-59 years old. The tumor is located in the left frontal region. On histology it is benign, transitional type of meningiomas.
Insights
Meningiomas, common brain tumors, are most frequent in women aged 50-59. The typical meningioma is a benign, transitional type, often found in the left frontal region.
Area of Science:
- Neurosurgery and Neuropathology
- Epidemiology of Neoplasms
Context:
- Meningiomas are primary intracranial tumors arising from meningeal arachnoidal cells.
- Understanding their demographic and histopathological characteristics is crucial for clinical management.
Purpose:
- To determine the age and sex distribution, common locations, frequency, and histological subtypes of meningiomas.
- To characterize the typical patient profile and tumor features.
Summary:
- This study analyzed 137 meningioma cases from 490 intracranial tumor patients.
- Meningiomas predominantly affect females (63%) in the 50-59 age group (37.2%).
- The most common type was benign transitional meningioma (59.1%), typically located frontally (36.5%) and on the left side (44.5%).
Impact:
- Findings establish a demographic profile for meningioma patients, aiding in diagnosis and risk assessment.
- Highlights the high prevalence of benign meningiomas, informing treatment strategies and prognosis.
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