Development of a collaborative program to provide extracorporeal membrane oxygenation for adults with refractory

David A Turner1, Walter L Williford, Michelle A Peters

  • 1Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke Children's Hospital, Duke University Medical Center, Durham, NC, USA. David.Turner@Duke.edu

Insights

A rapid adult extracorporeal membrane oxygenation (ECMO) program was developed during the pH1N1 pandemic to treat severe hypoxemia. This demonstrates a healthcare system

Area of Science:

  • Critical Care Medicine
  • Pandemic Response
  • Extracorporeal Membrane Oxygenation (ECMO)

Background:

  • The pH1N1 influenza pandemic presented a critical need for advanced respiratory support in young adults with refractory hypoxemia.
  • Existing neonatal and pediatric extracorporeal membrane oxygenation (ECMO) programs highlighted the potential for adult application.

Purpose of the Study:

  • To describe the rapid development and implementation of a collaborative adult respiratory extracorporeal membrane oxygenation (ECMO) program.
  • To address the urgent healthcare demands posed by the pH1N1 pandemic, specifically for young adults with severe respiratory failure.

Main Methods:

  • A multidisciplinary and interdisciplinary approach was adopted to establish the adult ECMO program.
  • Key implementation steps included securing administrative support, fostering collaborative leadership, and conducting extensive educational initiatives.
  • Technical modifications were essential for adapting existing infrastructure to adult venovenous ECMO requirements.

Main Results:

  • An adult venovenous extracorporeal membrane oxygenation program was successfully implemented within an 8-week timeframe.
  • The program was developed in response to the successful use of ECMO in young adults with pH1N1-induced acute respiratory distress syndrome.

Conclusions:

  • The rapid development and successful implementation of the adult ECMO program demonstrate a healthcare system's ability to respond effectively to urgent public health crises.
  • This expansion successfully integrated all necessary components, complementing the established neonatal-pediatric ECMO services.
Abstract

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