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Updated: Jun 6, 2026
03:53
Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV
Published on: November 10, 2023
Pandemic influenza's 500th anniversary
David M Morens1, Jeffery K Taubenberger, Gregory K Folkers
1National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. dm260q@nih.gov
Summary
The first recognized influenza pandemic occurred in 1510. Significant progress in influenza diagnosis, prevention, control, and treatment has been made over five centuries, promising reduced future pandemic burdens.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The exact origin of human influenza virus infections and the first influenza pandemic remain unknown.
- Historical consensus identifies 1510 AD as the first documented recognition of a pandemic influenza event.
Observation:
- This review commemorates the 500th anniversary of the 1510 pandemic.
- It examines the circumstances surrounding the emergence of the 1510 pandemic.
- It assesses the advancements in understanding and managing influenza over five centuries.
Findings:
- Substantial progress has been achieved in recent decades concerning influenza diagnosis.
- Significant advancements have been made in the prevention and control of influenza.
- Effective treatments for influenza have been developed and improved.
Implications:
- Future influenza pandemics may be significantly mitigated through enhanced vaccines.
- Continued scientific and public health initiatives are crucial for reducing the global burden of influenza.
- Improved diagnostic and therapeutic strategies offer hope for better influenza management.
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