Related Experiment Video
Updated: Jun 6, 2026
06:59
Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
[A case of chondroblastoma arising from the temporal bone]
Satoshi Tsutsumi1, Yumiko Mishima, Yasuomi Nonaka
1Department of Neurosurgery, Juntendo University Urayasu Hospital, Chiba, Japan.
No Shinkei Geka. Neurological Surgery
|November 18, 2010
Summary
A rare temporal bone chondroblastoma caused hearing loss and facial nerve issues in a 33-year-old male. Surgical resection was successful, highlighting chondroblastoma as a key differential diagnosis for temporal bone tumors.
Area of Science:
- Neuro-oncology
- Otorhinolaryngology
- Surgical Pathology
Background:
- Temporal bone tumors are rare and can present with diverse symptoms.
- Early diagnosis and surgical intervention are crucial for favorable outcomes.
Observation:
- A 33-year-old male presented with progressive left ear hearing disturbance, facial nerve paresis, and external auditory canal stenosis.
- Neuroimaging revealed a large temporal bone tumor with calcification and extensive bony destruction.
- The tumor exhibited heterogeneous intensity on MRI, suggestive of a complex mass.
Findings:
- Gross total resection of the temporal bone tumor was achieved via frontotemporal craniotomy.
- Histopathological analysis confirmed the diagnosis of chondroblastoma.
- Postoperative facial nerve paresis transiently worsened but gradually resolved; hearing loss persisted.
Implications:
- Chondroblastoma should be considered in the differential diagnosis of temporal bone tumors.
- Surgical resection is a viable curative treatment for temporal bone chondroblastoma.
- This case underscores the importance of comprehensive evaluation for complex temporal bone lesions.
Related Concept Videos
01:24Bone Formation by Endochondral Ossification
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
01:27Growth of Cartilage and Bone Tissue
Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
01:27Cranial Bones: Lateral View
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
01:22Sutures of the Skull
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
01:27Compact Bone
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
01:29Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...