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Updated: Jun 6, 2026

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IRF6 mutations in mixed isolated familial clefting.

Katherine D Rutledge1, Christina Barger, John H Grant

  • 1Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, USA.

American Journal of Medical Genetics. Part A
|November 18, 2010
PubMed
Summary

Mutations in the interferon regulatory factor 6 (IRF6) gene are linked to van der Woude syndrome. This study identifies IRF6 mutations in families with mixed oro-facial clefting, suggesting IRF6 testing is valuable for these cases.

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