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Updated: Jun 6, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
Tris(indolyl)methene molecule as an anion receptor and colorimetric chemosensor: tunable selectivity and sensitivity
Litao Wang1, Xiaoming He, Yong Guo
1Key Laboratory of Chemistry of Northwestern Plant Resources, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China.
Abstract:
Simple tris(indolyl)methene receptors 1-3 containing conjugated bisindole skeletons have been designed and synthesized. The anion binding and sensing properties have been studied using UV-vis spectroscopy and (1)H NMR titration technique. Compared with 3,3'-bis-indolyl phenylmethene (4), tris(indolyl)methene receptors could highly selectively detect F(-) based on two stages of proton transfer, along with stepwise drastic color changes. The introduction of the electron withdrawing or donating groups into indole unit, which tunes the acidities of the hydrogen bond sites, partially enhanced or inhibited the occurrence of the deprotonation of receptor and has a positive effect on the selectivity and sensitivity of such "proton-transfer" chemosensors for anions.
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