Related Experiment Video

Updated: Jun 6, 2026

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells
08:30

Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells

Published on: January 7, 2020

[Single-cell analysis for the specification of germ cell fate in mice]

Yasuhide Ohinata, Kazuki Kurimoto, Yukihiro Yabuta

    Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme
    |November 25, 2010
    PubMed
    Abstract

    No abstract available in PubMed .

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    Determination01:51

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    During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...