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Updated: Jun 6, 2026
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Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
[Focus on the challenge of basic research on corneal tissue engineering]
1Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Eye Institute and Affiliated Xiamen Eye Center, Xiamen University, Xiamen 361005, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|November 25, 2010
Summary
Corneal tissue engineering has advanced significantly, yet challenges remain in selecting materials and cells for clinical application. Future research aims to overcome these hurdles for engineered cornea therapies.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Ophthalmology
Context:
- Corneal tissue engineering has seen substantial progress over the last 20 years.
- Significant knowledge has been acquired regarding seed cells, carrier materials, and reconstruction strategies.
Purpose:
- To review the advancements and persistent challenges in corneal tissue engineering.
- To identify key areas for future research to enable clinical translation.
Summary:
- Progress in corneal tissue engineering involves seed cells, biomaterials, and reconstruction techniques.
- Challenges persist in selecting optimal carriers and cells, standardizing methods, and evaluating clinical outcomes.
- Future research should focus on addressing these fundamental questions for clinical application.
Impact:
- Highlights the current state and future directions of corneal tissue engineering.
- Identifies critical research gaps for the development of engineered cornea treatments.
- Aims to guide future studies toward successful clinical translation of tissue-engineered corneas.
