Autoimmune oral mucosal diseases: clinical, etiologic, diagnostic, and treatment considerations

James J Sciubba1

  • 1The Milton J. Dance Head & Neck Center, The Greater Baltimore Medical Center, 6569 North Charles Street, Baltimore, MD 21204, USA. jsciubba@gbmc.org

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Autoimmune Disorders

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Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors

Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI)  tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining. Bicarbonate,...
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