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Related Concept Videos

Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
Stress and Mental Health01:30

Stress and Mental Health

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Physiological Foundation of Stress01:24

Physiological Foundation of Stress

Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...

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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

Stress and autoimmunity.

Courtney J McCray1, Sandeep K Agarwal

  • 1Division of Rheumatology and Clinical Immunogenetics, Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin Street, MSB 5.278, Houston, TX 77030, USA.

Immunology and Allergy Clinics of North America
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Stress reduction interventions positively impact autoimmune disease patients. Managing stress is crucial for rheumatoid arthritis treatment, acting as a key therapeutic option.

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Area of Science:

  • Immunology
  • Psychoneuroimmunology
  • Rheumatology

Background:

  • Stress significantly impacts patients with autoimmune diseases.
  • The interplay between stress and autoimmune conditions requires clinical attention.
  • Rheumatoid arthritis (RA) is a chronic autoimmune disease influenced by various factors.

Purpose of the Study:

  • To evaluate the role of stress as a trigger and modulator in rheumatoid arthritis.
  • To assess stress reduction interventions as a potential treatment for RA.
  • To emphasize the importance of a multidimensional treatment approach for RA patients.

Main Methods:

  • Literature review on stress, autoimmune diseases, and rheumatoid arthritis.
  • Analysis of stress as a trigger and modulator in RA pathogenesis.
  • Evaluation of evidence for stress reduction techniques in RA management.

Main Results:

  • Stress can initiate and exacerbate rheumatoid arthritis symptoms.
  • Stress reduction interventions demonstrate therapeutic potential in RA.
  • Integrating stress management into RA treatment plans is beneficial.

Conclusions:

  • Stress is a significant factor in rheumatoid arthritis.
  • Stress reduction interventions offer a viable complementary treatment for RA.
  • A holistic approach incorporating stress management is essential for effective RA care.