Related Experiment Video
Updated: Jun 6, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
Published on: April 23, 2014
[Adherence and cognitive performance in schizophrenia]
A Spiekermann1, M Schulz, J Behrens
1Abteilung für Forschung, Qualitätssicherung und Dokumentation, Klinik für Psychiatrie und Psychotherapie Bethel, Bielefeld. alexa_spiekermann@gmx.de
Background:
It is known that many patients with schizophrenia show non-adherence with regard to antipsychotic medication. Furthermore, many studies indicate cognitive deficits in schizophrenic patients. In this review, we compare the results of studies examining the relationship of non-adherence and cognitive performance.
Method:
Based on a systematic literature review, the impact of cognitive performance on the adherence behaviour of patients with schizophrenia was examined.
Results:
We found 18 studies analysing the impact of cognitive performance on adherence behaviour. Most studies indicated that patients with stronger cognitive impairments show lower adherence behaviour. Possible causal mechanisms are discussed.
Related Concept Videos
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Drug Therapy
Antianxiety Medications
Schizophrenia
Psychological and Sociocultural Causes of Schizophrenia
Psychosis: Goals of Pharmacotherapy
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
