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Related Experiment Videos

Enterotoxemia in two foals.

C W Dickie, D L Klinkerman, R J Petrie

    Journal of the American Veterinary Medical Association
    |August 1, 1978
    PubMed
    Summary

    Two Quarter Horse foals died from enterotoxemia, a condition caused by Clostridium perfringens type C. The bacteria produced alpha and beta toxins, leading to intestinal damage and foal death.

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    Area of Science:

    • Veterinary Pathology
    • Microbiology

    Background:

    • Enterotoxemia is a serious condition in foals.
    • Clostridium perfringens is a known cause of enterotoxemia.

    Observation:

    • Two Quarter Horse foals from different premises presented with fatal enterotoxemia.
    • Post-mortem analysis revealed Clostridium perfringens type C in the intestines of both foals.

    Findings:

    • Mouse protection tests confirmed the presence of Clostridium perfringens alpha and beta toxins in the affected foals.
    • Histological examination showed significant intestinal hemorrhage, necrosis, and a high bacterial load of C. perfringens.

    Implications:

    • This study confirms Clostridium perfringens type C as a cause of enterotoxemia in Quarter Horse foals.
    • Understanding the specific toxins involved can aid in developing targeted prevention and treatment strategies.