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Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
Cardiovascular diseases and the liver
Ilan S Weisberg1, Ira M Jacobson
1Division of Gastroenterology and Hepatology, Weill Cornell Medical Center, New York Presbyterian Hospital, 1305 York Avenue, 4th Floor, New York, NY 10021, USA.
Insights
The liver
Area of Science:
- Cardiovascular Medicine
- Hepatology
- Hepatic Blood Flow Dynamics
Background:
- The liver possesses a unique dual blood supply from the portal vein and hepatic artery, conferring resistance to minor circulatory issues.
- Hepatic complications associated with common cardiovascular disorders are prevalent in clinical practice.
- Understanding liver circulation is crucial for diagnosing and managing cardiovascular-related liver diseases.
Purpose of the Study:
- To review the pathophysiology of hepatic blood flow, considering both macro- and microcirculation.
- To provide a detailed appraisal of ischemic hepatitis and congestive hepatopathy.
- To discuss other hepatic conditions resulting from impaired cardiovascular function.
Main Methods:
- Review of existing literature on liver physiology and cardiovascular pathology.
- Analysis of the interplay between systemic circulation and hepatic perfusion.
- Synthesis of information on specific hepatic conditions linked to cardiovascular disease.
Main Results:
- The liver's dual blood supply offers some protection, but cardiovascular disorders frequently impact liver function.
- Ischemic hepatitis and congestive hepatopathy are significant hepatic manifestations of cardiac dysfunction.
- Various other less common hepatic conditions can arise due to impaired cardiovascular health.
Conclusions:
- Cardiovascular disorders commonly lead to hepatic manifestations requiring clinical attention.
- Impaired hepatic blood flow due to cardiovascular disease results in conditions like ischemic hepatitis and congestive hepatopathy.
- A comprehensive understanding of hepatic circulation and cardiovascular interactions is essential for effective patient management.
Abstract:
The dual blood supply of the liver, originating from the portal vein and the hepatic artery, makes it relatively resistant to minor circulatory disturbances. However, hepatic manifestations of common cardiovascular disorders are frequently encountered in both the inpatient and outpatient setting. Beginning with the macro- and microcirculation of the liver, this article reviews the pathophysiology of hepatic blood flow and gives a detailed appraisal of ischemic hepatitis, congestive hepatopathy, and other less common hepatic conditions that arise when cardiovascular function is impaired.
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