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Updated: Jun 6, 2026

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A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
Published on: August 21, 2021
Closure of mesenteric defect can lead to decrease in internal hernias after Roux-en-Y gastric bypass.
Nestor de la Cruz-Muñoz1, Juan C Cabrera, Melissa Cuesta
1Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA. ndelacruz@med.miami.edu
Summary
Closing mesenteric defects during Roux-en-Y gastric bypass significantly reduces internal hernia (IH) risk. This surgical technique prevents serious complications like bowel obstruction, improving patient outcomes.
Area of Science:
- Bariatric Surgery
- Minimally Invasive Surgery
- Surgical Complications
Background:
- Internal hernia (IH) is a known complication after Roux-en-Y gastric bypass (RYGB).
- There is ongoing debate regarding the necessity and efficacy of closing mesenteric defects to prevent IH.
- Previous studies report variable rates of IH and conflicting data on closure effectiveness.
Purpose of the Study:
- To evaluate the impact of closing the jejunojejunal anastomotic mesenteric defect on the incidence of internal hernia (IH) after RYGB.
- To compare IH rates in patients before and after the implementation of routine mesenteric defect closure.
Main Methods:
- Retrospective review of 2079 RYGB procedures performed between 2001 and 2009.
- Comparison of IH incidence between two groups: pre-September 2003 (defects not closed) and post-September 2003 (defects closed with permanent suture).
- Chi-square analysis was used to determine statistical significance.
Main Results:
- A significant reduction in IH incidence was observed after implementing mesenteric defect closure (1.0% vs 10%, P <.001).
- In the group with closed defects, only 1 IH occurred (at Petersen's defect), compared to 37 IHs in the group with open defects.
- The incidence of IH at the jejunojejunal mesenteric defect dropped from 10% to 0% after closure.
Conclusions:
- Routine closure of mesenteric defects during RYGB significantly decreases the incidence of internal hernias.
- Internal hernias can manifest acutely with obstruction or chronically with intermittent pain.
- Closing mesenteric defects is a crucial step in preventing IH after RYGB.
