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Updated: Jun 6, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Interneuronal membrane contacts and syncytial perforations in CA2 hippocampal area after brain trauma
N M Paramonova1, O S Sotnikov, T V Krasnova
1Laboratory of Neuronfunctional Morphology and Physiology, I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg. Russia.
Abstract:
Membranes of pyramid neuron bodies located in CA2 hippocampal area were studied by electron microscopy after gunshot craniocerebral injury. In control group, asynaptic contacts and interneuronal syncytial perforations forming from tight junctions were observed. Contacts and perforations increased in size after trauma. Their number was maximum after severe gunshot injury. They reached their maximal size on days 5-7 after the injury.

