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Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...

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Related Experiment Video

Updated: Jun 5, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

Clinical experience with bemiparin.

José Ignacio Abad Rico1, Francisco S Lozano Sánchez, Eduardo Rocha

  • 1Trauma and Orthopaedic Surgery Department, Carlos Haya Regional University Hospital, Málaga, Spain.

Drugs
|December 18, 2010
PubMed
Summary
This summary is machine-generated.

Bemiparin effectively prevents and treats venous thromboembolism (VTE) in surgical patients, showing comparable efficacy to other anticoagulants with fewer bleeding risks. Postoperative initiation offers significant benefits, including reduced costs and complications.

Related Experiment Videos

Last Updated: Jun 5, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

Area of Science:

  • Pharmacology and Therapeutics
  • Vascular Medicine
  • Surgical Thromboprophylaxis

Background:

  • Venous thromboembolism (VTE) poses a significant risk in moderate to high-risk surgical patients, with incidence rates of 15-60% without prophylaxis.
  • Effective thromboprophylaxis can reduce VTE incidence by over 70%.

Purpose of the Study:

  • To evaluate the efficacy and safety of subcutaneous bemiparin for VTE prevention and treatment in surgical patients.
  • To compare bemiparin with unfractionated heparin (UFH), enoxaparin, and warfarin in various clinical scenarios.

Main Methods:

  • Comparative studies evaluating bemiparin versus UFH, enoxaparin, and warfarin for VTE prophylaxis and treatment.
  • Analysis of VTE incidence, bleeding episodes, and cost-effectiveness.

Main Results:

  • Bemiparin demonstrated comparable efficacy to UFH and enoxaparin in VTE prevention, with significantly fewer bleeding episodes than UFH.
  • Postoperative initiation of bemiparin was as effective as preoperative initiation but with lower bleeding risk.
  • Bemiparin was more effective than IV UFH for acute DVT treatment and as effective as warfarin for secondary prevention.
  • Extended prophylaxis (4 weeks) in cancer patients significantly reduced VTE rates without increasing bleeding.
  • Outpatient treatment of acute VTE with bemiparin was effective and cost-saving compared to inpatient treatment.

Conclusions:

  • Subcutaneous bemiparin is an effective and well-tolerated agent for VTE prophylaxis and treatment in surgical patients.
  • Postoperative initiation of bemiparin offers advantages in terms of safety, cost-effectiveness, and reduced complications, particularly in patients with neuraxial anesthesia.
  • Bemiparin presents a favorable profile compared to UFH and enoxaparin, with potential cost savings and improved quality of life.