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Updated: Jun 5, 2026

Noninvasive, High-throughput Determination of Sleep Duration in Rodents
Published on: April 18, 2018
[The change of macular thickness of SAS before and after sleep]
Yuming Xie1, Shaojun Zhou, Xiuying Xie
1TCM Hospital of LiWan District Guangzhou 510060,Chian.
Purpose:
To observe the changes of macular thickness in patients with sleep apnea syndrome (SAS) before and after sleep.
Methods:
Thirty-two patients (63 eyes) diagnosed as SAS from August 2003 to January 2007 were enrolled. Macular thickness were measured using optical coherence tomography (OCT) at 11:00 to 12:00 evening (before sleep)and 20 to 30 minute after sleep, respectively.
Results:
The mean macular thickness was (123.00+/-19.98)um and (134.25+/-19.92)um before and after sleep, respectively. The mean difference was (11.25+/-9.04)um before and after sleep(t=9.878,p<0.05),95%CI(8.98,13.53)um.
Conclusions:
The macular thickness of SAS is increased in SAS patients, which may due to anoxia of SAS.

