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SAIL--a software system for sample and phenotype availability across biobanks and cohorts
Mikhail Gostev1, Julio Fernandez-Banet, Johan Rung
1Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. gostev@ebi.ac.uk
Bioinformatics (Oxford, England)
|December 21, 2010
Summary
The Sample avAILability system (SAIL) is a web-based tool for managing biological sample collections. It enhances resource integration by detailing sample and data availability, enabling efficient searching and annotation for millions of samples.
Area of Science:
- Bioinformatics
- Data Management
- Genomics
Background:
- Biological sample collections and biobank entries require efficient management and integration.
- Existing systems may lack flexibility in describing sample data and availability.
Purpose of the Study:
- To introduce the Sample avAILability system (SAIL), a web-based application for biological sample management.
- To facilitate resource integration by providing detailed information on sample and data availability.
Main Methods:
- Developed a web-based application with a flexible data structure.
- Enabled searching, browsing, and annotating of biobank entries.
- Supported the use of existing or custom vocabularies for data description.
Main Results:
- SAIL provides individual-level information on sample and data (phenotype, genetic, genomic) availability.
- Users can query samples using various parameters and logical expressions.
- The system is scalable to millions of samples and thousands of variables.
Conclusions:
- SAIL facilitates biological resource integration through detailed availability information.
- The system supports flexible data description and advanced querying capabilities.
- SAIL is an open-source solution designed for large-scale biobank data management.
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