Related Experiment Video
Updated: Jun 5, 2026

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
Diagnosis and treatment of major depressive disorder
Laili Soleimani1, Kyle A B Lapidus, Dan V Iosifescu
1Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place Box 1230, New York, NY 10029, USA.
Abstract:
Major depressive disorder is a common illness, particularly in patients with medical and neurologic conditions. This article summarizes current data on the epidemiology, diagnosis, and treatment of major depression, with special emphasis on the diagnosis and treatment of depression in medical and neurologic patients. We reviewed the role of pharmacotherapies, psychotherapies, somatic treatments, and alternative remedies and we included practical advice for clinician regarding the timing and sequence of these treatments, the role of standardized depression scales, and the criteria for referrals to specialty consultants.
Related Concept Videos
Antidepressant Drugs: MAOIs and Other Agents
Depressive Disorders: MDD and Dysthymia
Depression: Overview
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Antidepressant Drugs: Overview
Drug Therapy
Antianxiety Medications

