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Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA
Published on: May 2, 2018
Mold exposure and respiratory health in damp indoor environments
Ju-Hyeong Park1, Jean M Cox-Ganser
1Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Respiratory Disease Studies, Morgantown, West Virginia, USA. gzp8@cdc.gov
Abstract:
Almost all modern buildings experience at least minor, and sometimes serious, water damage during their life span. Excess moisture in buildings becomes a critical factor for mold (fungal) proliferation in nutrient-rich environments. As a result, building occupants may be exposed to increased levels of microbial agents such as fungal spores, cell fragments, cell wall components, or toxins. Such exposures may result in various diseases and symptoms, both respiratory and non-respiratory. Respiratory health complaints are common in damp buildings and have been more thoroughly studied than non-respiratory complaints. Respiratory diseases and symptoms which may be produced by exposure to indoor fungi include asthma development, exacerbation of asthma, hypersensitivity pneumonitis, cough, wheeze, dyspnea (shortness of breath), nasal and throat symptoms, and respiratory infections. In addition to these illnesses, rhinosinusitis and sarcoidosis in water-damaged building occupants are also drawing more scientific attention. In this article, we explore the evidence for adverse effects of fungal exposure on respiratory health in damp indoor environments and potential disease mechanisms related to the exposure.
Insights
Damp buildings promote mold growth, leading to fungal spore exposure. This exposure can cause various respiratory issues, including asthma and infections, impacting indoor air quality and occupant health.
Area of Science:
- Environmental Health
- Building Science
- Mycology
Background:
- Water damage is prevalent in modern buildings, creating environments conducive to fungal proliferation.
- Building occupants can be exposed to microbial agents from indoor fungi, including spores and toxins.
Purpose of the Study:
- To explore the evidence linking fungal exposure in damp indoor environments to adverse respiratory health effects.
- To investigate potential disease mechanisms associated with indoor fungal exposure.
Main Methods:
- Literature review of studies on indoor fungi and respiratory health.
- Analysis of reported respiratory and non-respiratory symptoms in occupants of water-damaged buildings.
Main Results:
- Damp buildings facilitate fungal growth and subsequent exposure to microbial agents.
- Respiratory health complaints, such as asthma, cough, and infections, are common in damp buildings.
- Emerging evidence suggests links between fungal exposure and conditions like rhinosinusitis and sarcoidosis.
Conclusions:
- Fungal exposure in damp indoor environments poses significant risks to respiratory health.
- Understanding the mechanisms of fungal-induced respiratory diseases is crucial for public health.
- Mitigating moisture and fungal growth in buildings is essential for preventing adverse health outcomes.
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