N'-(5-Bromo-2-hydr-oxy-3-methoxy-benzyl-idene)isonicotinohydrazide
Acta Crystallographica. Section E, Structure Reports Online
|January 5, 2011
Summary
Researchers synthesized a novel brominated Schiff base, C(14)H(12)BrN(3)O(3), revealing a non-planar structure with intramolecular hydrogen bonding. The crystal structure shows molecules forming chains via intermolecular hydrogen bonds.
Area of Science:
- Organic Chemistry
- Crystallography
- Supramolecular Chemistry
Background:
- Schiff bases are versatile organic compounds with diverse applications.
- Halogenated organic molecules often exhibit unique chemical and physical properties.
- Understanding molecular structure and intermolecular interactions is crucial for materials science.
Purpose of the Study:
- To synthesize and characterize a novel Schiff base derivative.
- To investigate the molecular structure and conformation of the synthesized compound.
- To analyze the intermolecular interactions and crystal packing.
Main Methods:
- Synthesis of the title compound via condensation reaction.
- Single-crystal X-ray diffraction analysis to determine molecular and crystal structure.
- Spectroscopic methods for characterization (implied, not explicitly stated in abstract).
Main Results:
- The title compound, C(14)H(12)BrN(3)O(3), was successfully synthesized.
- The molecule exhibits a non-planar conformation with a trans configuration around the C=N bond.
- An intramolecular O-H⋯N hydrogen bond was observed.
- The dihedral angle between the benzene and pyridine rings is 12.2°.
- Intermolecular N-H⋯N hydrogen bonds link molecules into chains along the c-axis.
Conclusions:
- The study successfully synthesized and characterized a novel brominated Schiff base.
- The molecular structure and crystal packing reveal specific non-planar and hydrogen-bonding features.
- The observed intermolecular interactions dictate the formation of one-dimensional chains in the crystal lattice.
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