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![Solid-phase Synthesis of [4.4] Spirocyclic Oximes](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58508.jpg&w=3840&q=50)
Solid-phase Synthesis of [4.4] Spirocyclic Oximes
Published on: February 6, 2019
5,5',7,7'-Tetra-meth-oxy-2,2'-ethano-1,1'-spiro-biindane
Wu-Xin Hu1, Jun-Fa Wei, Xian-Ying Shi
1School of Chemistry and Materials Science, Shannxi Normal University, Xi'an 710062, People's Republic of China.
This study details the molecular structure of C(23)H(26)O(4), revealing a significant dihedral angle between its benzene rings and specific conformations in its five-membered rings.
Area of Science:
- Organic Chemistry
- Crystallography
Background:
- Understanding the three-dimensional structure of organic molecules is crucial for predicting their properties and reactivity.
- Benzene rings and five-membered rings are common structural motifs in many organic compounds.
Purpose of the Study:
- To determine the precise three-dimensional molecular structure of the title compound, C(23)H(26)O(4).
- To analyze the spatial arrangement of the benzene rings and the conformation of the five-membered rings.
Main Methods:
- Single-crystal X-ray diffraction was employed to obtain the molecular structure.
- Analysis of bond lengths, bond angles, and dihedral angles was performed.
Main Results:
- The crystal structure of C(23)H(26)O(4) was determined.
- A dihedral angle of 83.7(6)° was observed between the two benzene rings.
- The five-membered rings were found to adopt chair conformations.
Conclusions:
- The study provides detailed structural information for C(23)H(26)O(4).
- The observed dihedral angle and ring conformations offer insights into the molecule's overall shape and potential interactions.
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