Related Experiment Video

Updated: Jun 5, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
09:26

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

Published on: November 17, 2011

3β-Hydroxy-friedelan-17β-carboxylic acid

Hai-Yan Chen, Cui-Wu Lin, Guang-Ying Chen

    Acta Crystallographica. Section E, Structure Reports Online
    |January 5, 2011
    PubMed

    More Related Videos

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile06:52

    Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile

    Published on: October 30, 2018

    A Strategy for Sensitive, Large Scale Quantitative Metabolomics14:18

    A Strategy for Sensitive, Large Scale Quantitative Metabolomics

    Published on: May 27, 2014

    Related Concept Videos

    Alkylation of β-Diester Enolates: Malonic Ester Synthesis01:14

    Alkylation of β-Diester Enolates: Malonic Ester Synthesis

    Malonic ester synthesis is a method to obtain α substituted carboxylic acids from ꞵ-diesters such as diethyl malonate and alkyl halides.
    Carboxylic Acid Derivatives: Overview01:15

    Carboxylic Acid Derivatives: Overview

    Carboxylic acid derivatives are formed by replacing the hydroxyl group of carboxylic acids with a different functional group. The most common carboxylic acid derivatives are:
    Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides01:16

    Nomenclature of Carboxylic Acid Derivatives: Acid Halides, Esters, and Acid Anhydrides

    Naming Acid Halides
    The IUPAC and common names of acid halides are derived from the corresponding carboxylic acids, by changing “ic acid” to “yl halide.” For example, as shown below, the IUPAC name ethanoyl chloride is derived from ethanoic acid, and the common name, acetyl chloride, is obtained from acetic acid.
    Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives01:35

    Loss of Carboxy Group as CO2: Decarboxylation of Malonic Acid Derivatives

    Just like β-keto acids—which upon thermal decarboxylation form ketones—β-dicarboxylic acids undergo decarboxylation to generate monocarboxylic acids with the liberation of carbon dioxide.
    Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Overview01:20

    Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Overview

    The Fischer esterification reaction was developed by the German chemist Emil Fischer in 1895. It is a condensation reaction between carboxylic acids and alcohols in an acidic medium to give esters and water.
    Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Mechanism01:13

    Carboxylic Acids to Esters: Acid-Catalyzed (Fischer) Esterification Mechanism

    Carboxylic acids react with alcohols to yield esters via an acid-catalyzed condensation reaction called Fischer esterification. This is a nucleophilic acyl substitution reaction that proceeds via a tetrahedral intermediate, where a water molecule is eliminated as the leaving group.