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Rapid diagnosis of tuberculous meningitis by polymerase chain reaction (PCR)
K Kaneko1, O Onodera, T Miyatake
1Department of Neurology, Niigata University, Japan.
Neurology
|October 1, 1990
Abstract:
Using a rapid and highly sensitive method for the diagnosis of tuberculous meningitis by polymerase chain reaction (PCR), we detected the Mycobacterium tuberculosis genome in CSF of 5 of 6 patients with clinically diagnosed tuberculous meningitis. The genome was not present in CSF from 10 patients with other types of meningitis and 10 normal controls.