Related Experiment Video
Updated: Jun 5, 2026
Multiple Intravenous Bolus Dosing and Invasive Hemodynamic Assessment in a Hypoxia-Induced Mouse Pulmonary Artery Hypertension Model
Published on: November 11, 2022
[Hemodynamics following + Gz stress in dog]
Aim:
To investigate the character of hemodynamics following + Gz stress in dog.
Methods:
Nine anesthesia dogs were exposed to 5, 7 and 9 + Gz stress, 90 s at peak G. Each animal was instrumented to measure left ventricular pressure, thoracic aorta pressure, iliac arterial pressure,common carotid artery flow (CCAF) and ECG.
Results:
(1) Heart rate, CCAF and blood pressure at any place increased. They were greater than those before + Gz stress (P < 0.05). (2) There were much more arrhythmias following high + Gz stress. Most of arrhythmias were junctional premature beats, ventricular premature beats. 80% arrhythmias occurred within 3 min following + Gz stress. (3) Blood pressure appeared the highest in the second min following + Gz stress.
Conclusion:
Great hemodynamic disturbance happened following high + Gz stress. There might were reperfusion arrhythmias. Protective measures should been noted following high + Gz stress.
