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Use of the Protease Fluorescent Detection Kit to Determine Protease Activity
Published on: August 4, 2009
An enzyme-sensitive probe for photoacoustic imaging and fluorescence detection of protease activity
Xiaohu Xia1, Miaoxin Yang, L Kyle Oetjen
1Department of Biomedical Engineering, Washington University in St Louis, MO 63130, USA. xia@biomed.wustl.edu
Nanoscale
|January 13, 2011
Abstract:
A gold nanocage and dye conjugate has been demonstrated for use with photoacoustic imaging and fluorescence detection of protease activity. The detection sensitivity could be maximized by using gold nanocages with a localized surface plasmon resonance peak away from the emission peak of the dye. These hybrids can be potentially used as multimodal contrast agents for molecular imaging.

