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Related Concept Videos

Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Tonsillitis II: Management01:26

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: Jun 5, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Synchronous bilateral tonsil squamous cell carcinoma.

Michelle M Roeser1, Eran E Alon, Kerry D Olsen

  • 1Department of Otorhinolaryngology, Mayo Clinic, Rochester, Minnesota, USA.

The Laryngoscope
|January 13, 2011
PubMed
Summary
This summary is machine-generated.

Simultaneous bilateral tonsil cancer is extremely rare. This case highlights the diagnostic role of PET scans and questions the need for bilateral tonsillectomy in HPV-positive oropharyngeal cancers.

Related Experiment Videos

Last Updated: Jun 5, 2026

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer
11:17

Thoracoscopic Extended Right Middle Plus Lower Sleeve Lobectomy for Non-Small-Cell Lung Cancer

Published on: February 27, 2026

Area of Science:

  • Otolaryngology
  • Oncology
  • Head and Neck Surgery

Background:

  • Squamous cell carcinoma of the palatine tonsil typically presents unilaterally.
  • Bilateral or contralateral metastasis is rare and usually indicates advanced disease.
  • Simultaneous bilateral tonsil carcinoma is exceedingly rare, with fewer than five cases reported.

Observation:

  • A 51-year-old male presented with bilateral palatine tonsil squamous cell carcinoma and metastatic neck disease.
  • Positron emission tomography (PET) scanning revealed asymmetric FDG uptake in both tonsils and neck.
  • The patient underwent bilateral robotic-assisted oropharyngectomy and bilateral neck dissections.

Findings:

  • Histopathology confirmed separate bilateral tonsillar carcinomas, both positive for human papillomavirus (HPV).
  • Metastatic disease was found in three cervical lymph nodes (one right, two left).
  • This case represents one of the few documented instances of simultaneous bilateral palatine tonsil SCCA.

Implications:

  • This rare presentation prompts reconsideration of surgical management for oropharyngeal cancers.
  • The HPV status of bilateral tonsil carcinomas may influence the decision for bilateral tonsillectomy.
  • Further research is needed to establish optimal treatment guidelines for such rare cases.