Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

Imaging Studies for Cardiovascular System III: X-Ray

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

Imaging Studies for Cardiovascular System V: CT

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

Imaging Studies for Cardiovascular System IV: CMRI

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effective thrombus extraction strategies in acute saphenous vein graft intervention.

BMJ case reports·2025

Same author

Use of Multiple Irradiations and Reference Materials as Comparators in Quality Control of Neutron Activation Analysis Data of Biological Samples.

Biological trace element research·2022

Same author

Non-invasive imaging of atherosclerosis regression with magnetic resonance to guide drug development.

Atherosclerosis·2016

Same author

Intravenous Furosemide for Acute Decompensated Congestive Heart Failure: What Is the Evidence?

Clinical pharmacology and therapeutics·2015

Same author

Clinical assessment of carotid atherosclerosis inflammation by positron emission tomography.

Current molecular medicine·2013

Same author

How to optimize the percutaneous treatment of bifurcated lesions: dedicated stents vs. provisional stenting.

Minerva cardioangiologica·2013

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

Imaging of atherosclerosis.

D R J Owen¹, A C Lindsay, R P Choudhury

¹Department of Experimental Medicine and Toxicology, Imperial College London, Hammersmith Hospital, London W12 0NN, United Kingdom. d.owen@imperial.ac.uk

Annual Review of Medicine

|January 14, 2011

Summary

Novel imaging techniques can now assess high-risk atherosclerotic plaque features, moving beyond traditional stenosis measurements. This review explores advanced methods for evaluating plaque characteristics and their role in thrombus formation.

More Related Videos

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Published on: May 26, 2015

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

Related Experiment Videos

Last Updated: Jun 5, 2026

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Three-Dimensional Imaging of Aortic Tissues in Atherosclerosis

Published on: October 25, 2024

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography

Published on: May 26, 2015

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

Published on: November 17, 2017

Area of Science:

Cardiovascular Medicine
Medical Imaging
Pathology

Background:

Atherosclerotic plaques leading to thrombus formation are not always identified by lumen stenosis.
Current clinical focus remains on quantifying plaque-induced stenosis.
High-risk plaque features like thin fibrous caps and necrotic cores are crucial but often overlooked by traditional methods.

Purpose of the Study:

To review and compare novel imaging modalities for evaluating atherosclerotic plaques.
To highlight the strengths and drawbacks of each imaging technique.
To discuss the quantification of atherosclerosis using advanced imaging.

Main Methods:

Review of current literature on advanced imaging techniques for atherosclerosis.
Analysis of modalities capable of probing plaque composition and morphology.
Comparison of imaging techniques based on their ability to detect high-risk plaque features.

Main Results:

Novel imaging techniques can identify key features of high-risk plaques, including thin fibrous caps, necrotic cores, macrophage infiltration, neovascularization, and intraplaque hemorrhage.
These advanced methods offer a more comprehensive evaluation than traditional stenosis quantification.
Each imaging modality presents unique advantages and limitations.

Conclusions:

Advanced imaging techniques are essential for a thorough evaluation of atherosclerosis.
These methods enable the assessment of vulnerable plaque characteristics, improving risk stratification.
Further research and clinical integration of these techniques are warranted for better patient outcomes.