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Updated: Aug 18, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 29, 2010
[Proteases and their inhibitors in patients with benign ovarian tumors]
Abstract:
Activities of neutral and weakly alkaline proteases, cathepsins, alpha 1-inhibitor of proteases were studied with simultaneous estimation of follicle stimulating, luteinizing hormones and progesterone in healthy persons and in patients with ovary benign tumors. A decrease in content of the peptide hormones was accompanied by an increase in proteolytic activity as well as by deterioration of these proteases ratio during various phases of the cycle; these alterations appear to be involved in pathogenesis of the disease.
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