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Updated: Jun 5, 2026

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Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration
Published on: May 31, 2018
Reparative regeneration of rat fetal liver after partial hepatectomy
A V Elchaninov1, G B Bolshakova
1Laboratory of Growth and Development, Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow, Russia. elchandrey@yandex.ru
Bulletin of Experimental Biology and Medicine
|January 18, 2011
Abstract:
A reproducible model of fetal liver regeneration was created. Resection of 20% liver was carried out in rat fetuses on day 17 of prenatal development. The organ weight was restored after 2 days at the expense of an increase in hepatocyte mitotic activity; cell hypertrophy was minor. After recovery, the cell composition of the operated liver did not differ from the control, i.e. the regeneration was organotypical.

