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Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Doppler Effect - II01:05

Doppler Effect - II

The Doppler effect has several practical, real-world applications. For instance, meteorologists use Doppler radars to interpret weather events based on the Doppler effect. Typically, a transmitter emits radio waves at a specific frequency toward the sky from a weather station. The radio waves bounce off the clouds and precipitation and travel back to the weather station. The radio frequency of the waves reflected back to the station appears to decrease if the clouds or precipitation are moving...
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Doppler Effect - I00:56

Doppler Effect - I

The Doppler effect and Doppler shift were named after the Austrian physicist and mathematician Christian Johann Doppler in 1842, who conducted experiments with both moving sources and moving observers. Consider an observer standing on a street corner, observing an ambulance with a siren sound passing by at a constant speed. The observer experiences two characteristic changes in the sound of the siren. Initially, the sound increases in loudness as the ambulance approaches and decreases in...
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:

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Related Experiment Video

Updated: Jun 5, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Swept-source based, single-shot, multi-detectable velocity range Doppler optical coherence tomography.

Panomsak Meemon, Jannick P Rolland

    Biomedical Optics Express
    |January 25, 2011
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new method for Phase-Resolved Doppler Optical Coherence Tomography (PR-DOCT) to improve flow visualization. The technique enhances the Velocity Dynamic Range (VDR), enabling detection of both fast and slow blood flow with greater accuracy.

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    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
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    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

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    Last Updated: Jun 5, 2026

    Doppler Optical Coherence Tomography of Retinal Circulation
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    Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
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    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
    11:21

    Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography

    Published on: January 15, 2013

    Area of Science:

    • Biomedical Optics
    • Medical Imaging
    • Fluid Dynamics

    Background:

    • Phase-Resolved Doppler Optical Coherence Tomography (PR-DOCT) visualizes flow dynamics within static structures.
    • The Velocity Dynamic Range (VDR) of PR-DOCT is limited by detectable Doppler phase shifts and acquisition time.
    • Existing PR-DOCT systems face challenges in detecting slow flow due to limitations in phase stability and ambiguity.

    Purpose of the Study:

    • To develop an improved acquisition scheme for PR-DOCT.
    • To extend the lower limit of the detectable Velocity Dynamic Range (VDR).
    • To maintain the maximum detectable velocity, thereby increasing the overall VDR.

    Main Methods:

    • Implemented a multi-scale measurement technique for simultaneous acquisition of multiple VDRs.
    • Developed a dual VDR DOCT system capable of real-time detection, processing, and display of two distinct Doppler maps.
    • Utilized a fixed VDR DOCT for velocities up to 10.9 mm/s and a variable VDR DOCT for velocities down to 11.3 μm/s.

    Main Results:

    • The novel acquisition scheme effectively extends the lower limit of the detectable VDR.
    • The dual VDR DOCT system successfully visualized slow flow undetectable by conventional methods.
    • Demonstrated real-time Doppler imaging of an African frog tadpole using the dual-VDR DOCT system.

    Conclusions:

    • The multi-scale measurement technique significantly enhances the overall detectable VDR of PR-DOCT systems.
    • This advancement allows for more comprehensive visualization of diverse flow velocities.
    • The dual VDR DOCT system offers a powerful tool for studying microcirculation and other slow flow phenomena.