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Updated: Jun 5, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Stable absolute flow estimation with Doppler OCT based on virtual circumpapillary scans.

Amardeep S G Singh¹, Christoph Kolbitsch, Tilman Schmoll

¹Group of Biomedical Optics, Center of Medical Physics and Biomedical Engineering, Medical University Vienna, Waehringerstrasse 13, 1090 VIENNA, Austria.

Biomedical Optics Express

|January 25, 2011

Summary

This summary is machine-generated.

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This study introduces a new method for accurately measuring retinal blood flow using Doppler optical coherence tomography. The technique corrects for vessel angle, improving quantitative blood flow analysis in the human eye.

Area of Science:

Ophthalmology
Biomedical Engineering
Medical Imaging

Background:

Doppler optical coherence tomography (OCT) enables in vivo quantitative blood flow measurement.
OCT velocity measurements are limited to the axial component, requiring angle correction for accurate flow assessment.

Purpose of the Study:

To present a novel method for quantitative blood flow analysis in retinal vessels.
To improve accuracy by directly extracting vessel angle from OCT volume scans.

Main Methods:

A novel approach using registration of circumpapillary scans to a reference volume scan.
Direct extraction of vessel angle from the OCT volume data.
Phase unwrapping and interpolation assuming a parabolic flow profile.

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Last Updated: Jun 5, 2026

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Blood Flow Imaging with Ultrafast Doppler

Blood Flow Imaging with Ultrafast Doppler

Published on: October 14, 2020

Main Results:

Demonstrated repeatability of the method with coefficients of variation of 3-8% for average velocity.
Successfully applied to various retinal vessels.
Presented results for pulsatility and resistance index.

Conclusions:

The developed method allows for accurate, in vivo, quantitative blood flow assessment in the human retina.
The technique shows high repeatability, supporting its clinical applicability.
This advancement aids in understanding retinal hemodynamics and diagnosing related conditions.